Basket Trial Update from Theresa Beech
As many of you know, I’ve been doing osteo genetics research since my son Daniel was on hospice for osteo in spring, 2016. One outcome of my research showed very clearly that osteosarcoma has distinct genetic subcategories, and a doc at UCSF has showed that for at least some of these subcategories, the tumors will respond to genetically targeted therapy (not all of the subcategories have been tested) and that using a targeted agent in the wrong sub-type of tumor leads to no response.
There has been a lot of background work going on over the last 8 months. Now, on November 15-16, about 20 of the leading osteosarcoma docs and researchers from around the US will be gathering in DC for a 2 day meeting to define the clinical trial protocol for the Relapsed/Refractory Osteosarcoma Basket Trial. This trial is based upon my research and that of a doc at UCSF.
8 months seems like a really long time. For a family with a child on treatment it is a lifetime, the difference between life and death. But in pediatric oncology, I’ve been told that it usually takes 12-18 months to get to this point from the start of an idea. 8 months is apparently very quick.
Although for many, this trial comes too late (like it does for my Daniel), the participation of so many osteosarcoma families in this registry (120 and counting) has been absolutely critical to changing how osteosarcoma is thought of by the docs and researchers. Without everyone’s participation, my research would not be possible, and this trial would not be happening.
This trial is a direct, tangible result of patients and families participating in a clinical study. Individually, we are very limited in what we can accomplish. Together, we can move mountains and change the minds of doctors and researchers around the country, and ultimately around the world.
Thank you from the bottom of my heart.
Because of Daniel, Inc.